# Publications Search Within Results Search Within Results search ## 352 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 352 results Download 352 citations download- [BibTeX](/node/1560751/export?format=bibtex) - [EndNote X3 XML](/node/1560751/export?format=endnote8) - [EndNote 7 XML](/node/1560751/export?format=endnote7) - [Endnote tagged](/node/1560751/export?format=tagged) - [Marc](/node/1560751/export?format=marc) - [PubMedId](/node/1560751/export?format=pubmed_id) - [RIS](/node/1560751/export?format=ris) ### 2017 Wong, W., A.D. Griggs, R. F. Daniels, S. F. Schaffner, D. Ndiaye, A.K. Bei, A.B. Deme, et al. 2017. “[Genetic Relatedness Analysis Reveals the Cotransmission of Genetically Related Plasmodium Falciparum Parasites in Thiès, Senegal.](/publications/genetic-relatedness-analysis-reveals-cotransmission-genetically-related)”. *Genome Medicine*. Wong, W., A.D. Griggs, R. F. Daniels, S. F. Schaffner, D. Ndiaye, A.K. Bei, A.B. Deme, et al. 2017. “[Genetic Relatedness Analysis Reveals the Cotransmission of Genetically Related Plasmodium Falciparum Parasites in Thiès, Senegal.](/publications/genetic-relatedness-analysis-reveals-cotransmission-genetically-related)”. *Genome Medicine*. - add\_circle\_outline do\_not\_disturb\_on Abstract As public health interventions drive parasite populations to elimination, genetic epidemiology models that incorporate population genomics can be powerful tools for evaluating the effectiveness of continued intervention. However, current genetic... Volkman, Sarah, Jonathan Herman, Amanda Lukens, and Daniel Hartl. 2017. “[Genome Wide Association Studies of Drug-Resistance Determinants.](/publications/genome-wide-association-studies-drug-resistance-determinants)”. *Trends in Parasitology* 33 (3): 214-30. Volkman, Sarah, Jonathan Herman, Amanda Lukens, and Daniel Hartl. 2017. “[Genome Wide Association Studies of Drug-Resistance Determinants.](/publications/genome-wide-association-studies-drug-resistance-determinants)”. *Trends in Parasitology* 33 (3): 214-30. - add\_circle\_outline do\_not\_disturb\_on Abstract Population genetic strategies that leverage association, selection, and linkage have identified drug-resistant loci. However, challenges and limitations persist in identifying drug-resistance loci in malaria. In this review we discuss the genetic basis... ### 2016 Rice, Benjamin, Christopher Golden, Evelin Jean Gasta Anjaranirina, Carolina Mastella Botelho, Sarah Vokman, and Daniel Hartl. 2016. “[Genetic Evidence That the Makira Region Is a Hotspot of Plasmodium Falciparum Transmission in Northeastern Madagascar. ](/publications/genetic-evidence-makira-region-hotspot-plasmodium-falciparum-transmission)”. *Malaria Journal*. Rice, Benjamin, Christopher Golden, Evelin Jean Gasta Anjaranirina, Carolina Mastella Botelho, Sarah Vokman, and Daniel Hartl. 2016. “[Genetic Evidence That the Makira Region Is a Hotspot of Plasmodium Falciparum Transmission in Northeastern Madagascar. ](/publications/genetic-evidence-makira-region-hotspot-plasmodium-falciparum-transmission)”. *Malaria Journal*. - add\_circle\_outline do\_not\_disturb\_on Abstract Background: Encouraging advances in the control of Plasmodium falciparum malaria have been observed across much of Africa in the past decade. However, regions of high relative prevalence and transmission that remain unaddressed or unrecognized provide a... Ogbunugafor, C.B., and Hartl D.L. 2016. “[A New Take on John Maynard Smith’s Concept of Protein Space for Understanding Molecular Evolution.](/publications/new-take-john-maynard-smiths-concept-protein-space-understanding-molecular)”. *PLOS Computational Biology*. Ogbunugafor, C.B., and Hartl D.L. 2016. “[A New Take on John Maynard Smith’s Concept of Protein Space for Understanding Molecular Evolution.](/publications/new-take-john-maynard-smiths-concept-protein-space-understanding-molecular)”. *PLOS Computational Biology*. - add\_circle\_outline do\_not\_disturb\_on Abstract Molina-Cruz, Alvaro, Martine M. Zilversmit, Daniel E. Neafsey, Daniel L. Hartl, and Carolina Barillas-Mury. 2016. “[Mosquito Vectors and the Globalization of Plasmodium Falciparum Malaria](/publications/mosquito-vectors-and-globalization-plasmodium-falciparum-malaria)”. *Annual Reviews* 50: 447-65. Molina-Cruz, Alvaro, Martine M. Zilversmit, Daniel E. Neafsey, Daniel L. Hartl, and Carolina Barillas-Mury. 2016. “[Mosquito Vectors and the Globalization of Plasmodium Falciparum Malaria](/publications/mosquito-vectors-and-globalization-plasmodium-falciparum-malaria)”. *Annual Reviews* 50: 447-65. - add\_circle\_outline do\_not\_disturb\_on Abstract *Plasmodium falciparum* malaria remains a devastating public health problem. Recent discoveries have shed light on the origin and evolution of *Plasmodium* parasites and their interactions with their vertebrate and mosquito hosts. *P. falciparum* malari... Sackton, Timothy B., and Daniel L. Hartl. 2016. “[Genotypic Context and Epistasis in Individuals and Populations](/publications/genotypic-context-and-epistasis-individuals-and-populations)”. *Cell* 166 (2): 279-87. Sackton, Timothy B., and Daniel L. Hartl. 2016. “[Genotypic Context and Epistasis in Individuals and Populations](/publications/genotypic-context-and-epistasis-individuals-and-populations)”. *Cell* 166 (2): 279-87. - add\_circle\_outline do\_not\_disturb\_on Abstract Genes encode components of coevolved and interconnected networks. The effect of genotype on phenotype therefore depends on genotypic context through gene interactions known as epistasis. Epistasis is important in predicting phenotype from genotype for an... Lienard, Marjorie A., Luciana O. Araipe, and Daniel L. Hartl. 2016. “[Neighboring Genes for DNA-Binding Proteins Rescue Male Sterility in Drosophila Hybrids](/publications/neighboring-genes-dna-binding-proteins-rescue-male-sterility-drosophila)”. *PNAS* . Lienard, Marjorie A., Luciana O. Araipe, and Daniel L. Hartl. 2016. “[Neighboring Genes for DNA-Binding Proteins Rescue Male Sterility in Drosophila Hybrids](/publications/neighboring-genes-dna-binding-proteins-rescue-male-sterility-drosophila)”. *PNAS* . - add\_circle\_outline do\_not\_disturb\_on Abstract Crosses between closely related animal species often result in male hybrids that are sterile, and the molecular and functional basis of genetic factors for hybrid male sterility is of great interest. Here, we report a molecular and functional analysis of... Rodrigues, Joao V., Shimon Bershtein, Anna Li, Elena R. Lozovsky, Daniel L. Hartl, and EugeneI. Shakhnovich. 2016. “[Biophysical Principles Predict Fitness Landscapes of Drug Resistance](/publications/biophysical-principles-predict-fitness-landscapes-drug-resistance)”. *Proceedings of the National Academy of Sciences of the United States of America* 113 (11). Rodrigues, Joao V., Shimon Bershtein, Anna Li, Elena R. Lozovsky, Daniel L. Hartl, and EugeneI. Shakhnovich. 2016. “[Biophysical Principles Predict Fitness Landscapes of Drug Resistance](/publications/biophysical-principles-predict-fitness-landscapes-drug-resistance)”. *Proceedings of the National Academy of Sciences of the United States of America* 113 (11). - add\_circle\_outline do\_not\_disturb\_on Abstract Fitness landscapes of drug resistance constitute powerful tools to elucidate mutational pathways of antibiotic escape. Here, we developed a predictive biophysics-based fitness landscape of trimethoprim (TMP) resistance for *Escherichia coli* dihydrofolate... Ogbunugafor, C.B., C.S Wylie, Diakite, D. M. Weinreich, and D. L. Hartl. 2016. “[Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance](/publications/adaptive-landscape-environment-interactions-dictate-evolutionary-dynamics)”. *PLOS Computational Biology*. Ogbunugafor, C.B., C.S Wylie, Diakite, D. M. Weinreich, and D. L. Hartl. 2016. “[Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance](/publications/adaptive-landscape-environment-interactions-dictate-evolutionary-dynamics)”. *PLOS Computational Biology*. - add\_circle\_outline do\_not\_disturb\_on Abstract The adaptive landscape analogy has found practical use in recent years, as many have explored how their understanding can inform therapeutic strategies that subvert the evolution of drug resistance. A major barrier to applications of these concepts is a... Ogbunugafor, C.B., and D. L. Hartl. 2016. “[A Pivot Mutation Impedes Reverse Evolution across an Adaptive Landscape for Drug Resistance in Plasmodium Vivax](/publications/pivot-mutation-impedes-reverse-evolution-across-adaptive-landscape-drug)”. *Malaria Journal* . Ogbunugafor, C.B., and D. L. Hartl. 2016. “[A Pivot Mutation Impedes Reverse Evolution across an Adaptive Landscape for Drug Resistance in Plasmodium Vivax](/publications/pivot-mutation-impedes-reverse-evolution-across-adaptive-landscape-drug)”. *Malaria Journal* . - add\_circle\_outline do\_not\_disturb\_on Abstract Background: The study of reverse evolution from resistant to susceptible phenotypes can reveal constraints on biological evolution, a topic for which evolutionary theory has relatively few general principles. The public health catastrophe of... ### 2015 Chang, and Hartl. (February) 2015. “[Recurrent Bottlenecks in the Malaria Life Cycle Obscure Signals of Positive Selection](/publications/recurrent-bottlenecks-malaria-life-cycle-obscure-signals-positive-selection)”. *Parasitology* 142 Suppl 1: S98-S107. Chang, and Hartl. (February) 2015. “[Recurrent Bottlenecks in the Malaria Life Cycle Obscure Signals of Positive Selection](/publications/recurrent-bottlenecks-malaria-life-cycle-obscure-signals-positive-selection)”. *Parasitology* 142 Suppl 1: S98-S107. - add\_circle\_outline do\_not\_disturb\_on Abstract SUMMARY Detecting signals of selection in the genome of malaria parasites is a key to identify targets for drug and vaccine development. Malaria parasites have a unique life cycle alternating between vector and host organism with a population bottleneck... Galinsky, Valim, Salmier, Thoisy, Musset, Legrand, Faust, et al. (January) 2015. “[COIL: A Methodology for Evaluating Malarial Complexity of Infection Using Likelihood from Single Nucleotide Polymorphism Data](/publications/coil-methodology-evaluating-malarial-complexity-infection-using-likelihood)”. *Malar J* 14: 4. Galinsky, Valim, Salmier, Thoisy, Musset, Legrand, Faust, et al. (January) 2015. “[COIL: A Methodology for Evaluating Malarial Complexity of Infection Using Likelihood from Single Nucleotide Polymorphism Data](/publications/coil-methodology-evaluating-malarial-complexity-infection-using-likelihood)”. *Malar J* 14: 4. - add\_circle\_outline do\_not\_disturb\_on Abstract BACKGROUND: Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. Complexity of infection (COI) is a useful parameter to estimate from patient blood samples because it is associated... - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [ Last page 30 ](?page=29 "Go to last page") - [ Next page chevron\_right ](?page=1 "Go to next page")