@article {538881,
	title = {Regulatory potential of nonautonomous mariner elements and subfamily crosstalk},
	journal = {Genetica},
	volume = {107},
	number = {1-3},
	year = {1999},
	note = {<p>De Aguiar, DHartl, D LengResearch Support, Non-U.S. Gov{\textquoteright}tResearch Support, U.S. Gov{\textquoteright}t, Non-P.H.S.Research Support, U.S. Gov{\textquoteright}t, P.H.S.NETHERLANDS2000/08/22 11:00Genetica. 1999;107(1-3):79-85.</p>},
	pages = {79-85},
	abstract = {<p>Two naturally occurring nonautonomous mariner elements were tested in vivo for their ability to down-regulate excision of a target element in the presence of functional mariner transposase. The tested elements were the peach element isolated from Drosophila mauritiana, which encodes a transposase that differs from the autonomous element Mos1 in four amino acid replacements, and the DTBZ1 element isolated from D. teissieri, which encodes a truncated protein consisting of the first 132 residues at the amino end of the normally 345-residue transposase. We provide evidence that the protein from the peach element does interact to down-regulate wildtype transposase, indicating that at least some nonautonomous elements in natural populations that retain their open reading frame may play a regulatory role. In contrast, our tests reveal at most a weak interaction between transposase from the autonomous Mos1 element and the truncated protein from DTBZ1, and none between Mos1 transposase and that from the distantly related mariner-like element Himar1 identified in the horn fly Haematobia irritans. Hence, the extent of regulatory crosstalk between mariner-like elements may be limited to closely related ones. The evolutionary implications of these results are discussed.</p>},
	keywords = {*DNA Transposable Elements, Animals, DNA-Binding Proteins/*genetics, Drosophila/*genetics, Evolution, Molecular, Regulatory Sequences, Nucleic Acid, Transposases/genetics},
	isbn = {0016-6707 (Print)0016-6707 (Linking)},
	author = {De Aguiar, D. and Hartl, D. L.}
}
