@article {539711,
	title = {Rapid evolution of male-biased gene expression in Drosophila},
	journal = {Proc Natl Acad Sci U S A},
	volume = {100},
	number = {17},
	year = {2003},
	note = {<p>Meiklejohn, Colin DParsch, JohnRanz, Jose MHartl, Daniel LengGM 60035/GM/NIGMS NIH HHS/Comparative StudyResearch Support, Non-U.S. Gov{\textquoteright}tResearch Support, U.S. Gov{\textquoteright}t, P.H.S.2003/08/09 05:00Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9894-9. Epub 2003 Aug 7.</p>},
	month = {Aug 19},
	pages = {9894-9},
	abstract = {<p>A number of genes associated with sexual traits and reproduction evolve at the sequence level faster than the majority of genes coding for non-sex-related traits. Whole genome analyses allow this observation to be extended beyond the limited set of genes that have been studied thus far. We use cDNA microarrays to demonstrate that this pattern holds in Drosophila for the phenotype of gene expression as well, but in one sex only. Genes that are male-biased in their expression show more variation in relative expression levels between conspecific populations and two closely related species than do female-biased genes or genes with sexually monomorphic expression patterns. Additionally, elevated ratios of interspecific expression divergence to intraspecific expression variation among male-biased genes suggest that differences in rates of evolution may be due in part to natural selection. This finding has implications for our understanding of the importance of sexual dimorphism for speciation and rates of phenotypic evolution.</p>},
	keywords = {*Biological Evolution, *Genes, Insect, *Sex, Animals, Drosophila melanogaster/genetics, Drosophila/*genetics, Female, Gene Expression Profiling, Male, Oligonucleotide Array Sequence Analysis, Sex Characteristics, Species Specificity},
	isbn = {0027-8424 (Print)0027-8424 (Linking)},
	author = {Meiklejohn, C. D. and Parsch, J. and Ranz, J. M. and Hartl, D. L.}
}
