@article {539751,
	title = {Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages},
	journal = {Gene},
	volume = {350},
	number = {2},
	year = {2005},
	note = {<p>Neafsey, Daniel EHartl, Daniel LengComparative StudyResearch Support, Non-U.S. Gov{\textquoteright}tResearch Support, U.S. Gov{\textquoteright}t, Non-P.H.S.Netherlands2005/04/12 09:00Gene. 2005 May 9;350(2):161-71. Epub 2005 Apr 7.</p>},
	month = {May 9},
	pages = {161-71},
	abstract = {<p>We describe the complete opsin gene families from the sequenced fugu and Tetraodon pufferfish genomes. We report the convergent loss of function of an anciently duplicated, functionally divergent RH2 or "green-sensitive" opsin gene in both pufferfish lineages, designated RH2-2. In fugu, RH2-2 apparently ceased to function very recently following a transposon-induced deletion that truncated the N-terminal 115 amino acids from the translated protein. Although a lack of frameshift or nonsense mutations in the fugu RH2-2 pseudogene suggests that the gene was lost very recently in this lineage, we were unable to detect any evidence of a selective sweep associated with the fixation of the truncated allele from population data. Interspecific comparison of the remaining fugu RH2-2 coding sequence paradoxically indicates that the gene was under strong purifying selection until the truncation occurred.</p>},
	keywords = {Amino Acid Sequence, Base Sequence, DNA/chemistry/genetics, Fish Proteins/genetics, Gene Duplication, Gene Expression, Genetic Variation, Molecular Sequence Data, Multigene Family/genetics, Phylogeny, Polymorphism, Genetic, Rod Opsins/*genetics, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, Species Specificity, Takifugu/*genetics, Tetraodontiformes/*genetics},
	isbn = {0378-1119 (Print)0378-1119 (Linking)},
	author = {Neafsey, D. E. and Hartl, D. L.}
}
