Citation:
Date Published:
Jun 13Abstract:
Comparison of the gene-expression profiles between adults of Drosophila melanogaster and Drosophila simulans has uncovered the evolution of genes that exhibit sex-dependent regulation. Approximately half the genes showed differences in expression between the species, and among these, approximately 83% involved a gain, loss, increase, decrease, or reversal of sex-biased expression. Most of the interspecific differences in messenger RNA abundance affect male-biased genes. Genes that differ in expression between the species showed functional clustering only if they were sex-biased. Our results suggest that sex-dependent selection may drive changes in expression of many of the most rapidly evolving genes in the Drosophila transcriptome.
Notes:
Ranz, Jose MCastillo-Davis, Cristian IMeiklejohn, Colin DHartl, Daniel LengComparative StudyResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.New York, N.Y.2003/06/14 05:00Science. 2003 Jun 13;300(5626):1742-5.